Osteoporosis and spinal fractures

  • Project Leader:
    • Dr P Dolan, Dr D J Annesley-Williams and Dr M A Adams, BSc, PhD
  • Location:
    • Department of Anatomy, University of Bristol and Department of Neuroradiology, Queen's Medical Centre, Nottingham
  • Grant awarded:
    • 21 April 2004
  • Start date:
    • 1 February 2005
  • End date:
    • 30 April 2007
  • Grant amount:
    • £90,335
  • Grant code:
    • AP0994

Severe age-related bone loss ("osteoporosis") affects one in two women and one in five men over the age of 50 in the UK. Those affected often sustain a fracture of one or more vertebrae of the spine, leading to a humped back ("senile kyphosis") which can be painful, disabling and distressing. A spinal fracture can mean severely limited activity and constant pain. Current treatments do little to alleviate chronic pain, and cannot prevent deformity.

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