With your help, the research we have funded has helped save and change so many children’s lives. Here are some of ways research is making a difference.
University Department of Clinical Neurosciences, Royal Free and University College Medical School, London
Grant awarded
19 May 2000
Start date
4 September 2000
End date
3 November 2003
Grant amount
£136,818.00
Grant code
SF0890
Hereditary spastic paraparesis is a genetic condition causing weakness and stiffness of the legs, affecting approximately 1 in 10,000 people. Dr Wilkinson aims to identify new genes and characterise mutations within known genes which cause a particular form of this condition. He will also study the effect of these genes on cell function. This work should help us to understand the mechanisms of nerve cell death in the spinal cord. It should also improve genetic counselling and testing and may lead to new spasticity treatments.
Printer-friendly version
Send to friend
