Bone healing using cell therapy

Location: Anatomy Department, School of Medicine, Queen’s University of Belfast, and Department of Orthopaedic Surgery and Trauma, Queen’s University of Belfast, Musgrave Park Hospital in conjunction with the Fracture Clinic, Royal Victoria Hospital, Belfast.
Amount: £93,924
Status: Research completed
Start Date: 7th August 2002
Finish Date: 6th August 2004
Grantholder: Dr G R Dickson PhD, MSc, MIBiol, CBiol, FIBMS, Professor D R Marsh MD, FRCS, Dr G Li and Miss C J Geddis MRCS.
Research worker: Miss C J Geddis

The healing of a broken bone is one of the most remarkable repair processes in the body since it results, not in a scar, but in the reformation of tissue similar to its original form. However, bone fractures fail to unite properly after more than 5 months of immobilisation in 5-10% of patients, causing much suffering and even disability. Some patients will heal with further immobilisation but others will require additional surgery and lengthy rehabilitation.

These researchers are working on a novel technique to help repair problem fractures. Bone forming cells, taken from the patient’s pelvis can be grown then injected into the site of the non-union to form bone. The aim is to further develop this technique because it is safer and easier than current treatments involving general anaesthetic and surgery.

Partly funded by the Drapers’ Company.

Dr Glenn Dickson (l) with Dr Mervyn McCaigue in the cell culture facility

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