Osteoporosis and spinal fractures

Location: Department of Anatomy, University of Bristol and Department of Neuroradiology, Queen’s Medical Centre, Nottingham
Amount: £90,335
Status: Research completed
Start Date: 1st February 2005
Finish Date: 30th April 2007
Grantholder: Dr P Dolan, Dr D J Annesley-Williams and Dr M A Adams, BSc, PhD
Research worker: Dr Luo, Mrs C Costigan and Dr N Iqbal

Severe age-related bone loss ("osteoporosis") affects 1 in 2 women and 1 in 5 men over the age of 50 in the U.K. Those affected often sustain a fracture of one or more vertebrae of the spine, leading to a humped back ("senile kyphosis") which can be painful, disabling and distressing. A spinal fracture can mean severely limited activity and constant pain. Current treatments do little to alleviate chronic pain, and cannot prevent deformity.

An osteoporotic fracture of the vertebrae

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