cystic fibrosis | Action Medical Research

cystic fibrosis

Cystic fibrosis: developing a new type of gene therapy

Research date: 1 October 2018 - 30 September 2021
Grant amount: £154,634.00

Around 10,400 people in the UK, including more than 4,000 children, are living with cystic fibrosis.1 It is an inherited condition, with a range of symptoms caused by a build-up of thick sticky mucus and affecting many organs. Sadly, two people with cystic fibrosis will lose their lives every week, with lung damage due to regular chest infections a big...

Cystic fibrosis: improving treatment for lung infections

Research date: 15 January 2018 - 14 January 2021
Grant amount: £179,835.00

Around 10,400 people in the UK – including over 4,000 children – are living with an inherited condition called cystic fibrosis.1 Sadly, two people will lose their lives to the disease every week.2 A major cause of illness and death is persistent chest infections with a bacterium called Pseudomonas aeruginosa. These form structures called...

Cystic fibrosis: protecting children from life-changing infections

Research date: 1 August 2017 - 15 March 2020
Grant amount: £185,269.00

Around 10,800 people in the UK – including over 4,000 children – have an inherited lung condition called cystic fibrosis (CF).1 Children with CF are susceptible to chest infections which can be difficult to treat, often persisting for the rest of a child’s life and reducing life expectancy. Dr Jo Fothergill, of the University of...

Developing safer tests for cystic fibrosis and spinal muscular atrophy during pregnancy

Research date: 1 May 2016 - 31 December 2018
Grant amount: £198,634.00

Professor Lyn Chitty’s team at Great Ormond Street Hospital and the UCL Institute of Child Health is developing safer ways to diagnose two genetic conditions in babies during pregnancy: cystic fibrosis, which affects over 10,000 people in the UK, and spinal muscular atrophy (SMA), which affects 2,000 to 2,500.1-3 Existing tests can’t be done...

Cystic fibrosis - developing a new type of inhaled treatment

Research date: 12 September 2014 - 11 September 2016
Grant amount: £149,062.00

Over 10,000 people in the UK – 70,000 worldwide – have cystic fibrosis.1-3 Many are children and young people. Symptoms include a persistent cough, shortness of breath and recurrent chest infections. Although life expectancy has been increasing for people with cystic fibrosis, many are still losing their lives to the condition, often because...

Cystic fibrosis: which babies are at highest risk of the most severe disease?

Research date: 1 May 2013 - 30 November 2016
Grant amount: £135,693.00

Over 9,000 people in the UK have cystic fibrosis (CF) – one of the most common, life-threatening inherited diseases.1 When babies are born with CF, it’s hard to predict how severe their illness will be. Dr Paul Aurora, at the University College London Institute of Child Health, is looking for ways to identify which children are at highest risk...

Other related information

Preventing infection in children with cystic fibrosis

Posted: 27 March 2017 13:30 pm
Children with cystic fibrosis are susceptible to chest infections which can be very difficult to treat. These can cause long-term ill health and reduce life expectancy. New research aims to diagnose infections sooner and prevent them from taking hold. Cystic fibrosis is a serious, inherited lung condition with no cure. It affects more than 4,000...

Easing the daily struggle of cystic fibrosis

Posted: 21 April 2015 15:42 pm
Professor Steve Hart of University College London is developing a new treatment for the incurable inherited disease cystic fibrosis. The aim is to protect the lungs, ease children’s breathing difficulties and reduce the number of chest infections. Each week in the UK, five people – mostly babies and young children – are diagnosed...

Study into new treatment for Cystic Fibrosis

Posted: 19 November 2014 11:57 am
Cystic fibrosis: developing a new type of inhaled therapy The children’s charity Action Medical Research and the Cystic Fibrosis Trust have joined forces to fund a laboratory study to develop a new, once-monthly, inhaled treatment for children with cystic fibrosis (CF). The total amount awarded for the new study, being led by Professor Steve...

Tracing the cause of a deadly infection

Posted: 21 March 2012 15:54 pm
Pseudomonas aeruginosa can be a dangerous bacterium and a leading cause of death among people with cystic fibrosis. Researchers funded by Action Medical Research have identified some of the reasons why it is so dangerous. The healthy among us have little to fear from Pseudomonas aeruginosa, but for some, infection is deadly. The bacterium can kill...
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