This research was completed on 31 July 2004
|Project Leader||Dr O W J Quarrell MD, FRCP, Dr A Dalton PhD, MRCPath, Mr A S Rigby BSc, MSc, C Stat and Dr J P Warner PhD, DipRCPath.|
|Location||Department of Clinical Genetics, North Trent Molecular Genetics Service and the Department of Paediatrics all at Sheffield Children's Hospital in conjunction with the Molecular Medicine Centre, Western General Hospital, Edinburgh.|
|Grant awarded||7 November 2002|
|Start date||1 February 2003|
|End date||31 July 2004|
We do not provide medical advice. If you would like more information about a condition or would like to talk to someone about your health, contact NHS Choices or speak to your GP. Please see our useful links page for some links to health information, organisations we are working with and other useful organisations. We hope you will find these useful. We are not responsible for the content of any of these sites.
Huntington’s disease (HD) is a serious neurodegenerative disorder, for which no effective treatment is available. It affects about 6,000 people in the UK and is inherited, so many more people know they are at risk of developing the condition. The gene for the disorder has been identified and it is possible for those at risk to take a test to see if they will develop HD in the future. Some results are difficult to interpret as they indicate that the person concerned may or may not develop the condition over the course of a lifetime: this is called reduced penetrance. This study aims to obtain anonymised details on the patients in the UK who have had such a result and determine the probability that an individual with such a result will develop the condition by a specific age. In future, this will improve the quality of information that can be given to those affected about the likelihood of developing the condition.