Motor Neurone Disease | Action Medical Research | Children's Charity | Children's Charity

Motor neurone disease

This research was completed on 31 March 2003

Project LeaderDr Anthony H Pullen, BSc, PhD
LocationSobell Department of Neurophysiology, Institute of Neurology, London.
Grant awarded22 October 1999
Start date1 January 2000
End date31 March 2003
Grant amount£111,273.00
Grant codeSP3498

We do not provide medical advice. If you would like more information about a condition or would like to talk to someone about your health, contact NHS Choices or speak to your GP. Please see our useful links page for some links to health information, organisations we are working with and other useful organisations. We hope you will find these useful. We are not responsible for the content of any of these sites.

The nerve cells which control muscles are called motor neurones. Motor neurone death occurs in a variety of conditions including spinal muscular atrophy and Motor Neurone Disease (MND). MND patients suffer a progressive muscle paralysis, the disease is invariably fatal and, so far, there is no way of preventing the process of nerve cell death. Dr Pullen will be trying to find out why these nerve cells die by investigating the blood of MND patients. This has been shown to contain specific active enzymes which might activate biochemical pathways which cause nerve cells to self-destruct. This research should help in the future design of suitable forms of treatment for diseases such as MND.

Help us spread the word