Pre-eclampsia - mechanisms of inflammation
This research was completed on 1 February 2003
|Project Leader||Professor C W G Redman, MB BChir, MA, FRCP, FRCOG and Dr I L Sargent, BSc, PhD, MA.|
|Location||Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Oxford.|
|Grant awarded||16 June 1999|
|Start date||2 February 2000|
|End date||1 February 2003|
We do not provide medical advice. If you would like more information about a condition or would like to talk to someone about your health, contact NHS Choices or speak to your GP. Please see our useful links page for some links to health information, organisations we are working with and other useful organisations. We hope you will find these useful. We are not responsible for the content of any of these sites.No other complication of pregnancy is so common and dangerous, both to mother and baby, as pre-eclampsia. Yet its cause is unknown and treatment depends on induced delivery to prevent its progression. It is difficult to predict and sometimes even to diagnose accurately. With support from Action Research these researchers have discovered that normal pregnancy excites an intense inflammatory response in the mother. Pre-eclampsia arises when the response is excessive. In this new project they will investigate what stimulates this inflammatory response and how it might run out of control. The added knowledge should enable prediction, diagnosis and treatment to be improved.