Pre-eclampsia - signalling inflammation
This research was completed on 4 July 2003
|Project Leader||Professor Christopher W G Redman, BA, MB BChir, MA, FRCP, FRCOG, Dr Ian L Sargent, BSc, PhD, MA, Dr Paul T-y Ayuk, MB BS, BSc and Dr Charles A R Boyd, BA, MSc, MA, BM BChir, DPhil|
|Location||Nuffield Department of Obstetrics and Gynaecology and the Women's Centre, John Radcliffe Hospital, Oxford in conjunction with the Department of Human Anatomy and Genetics, University of Oxford.|
|Grant awarded||22 October 1999|
|Start date||1 March 2000|
|End date||4 July 2003|
We do not provide medical advice. If you would like more information about a condition or would like to talk to someone about your health, contact NHS Choices or speak to your GP. Please see our useful links page for some links to health information, organisations we are working with and other useful organisations. We hope you will find these useful. We are not responsible for the content of any of these sites.Pre-eclampsia is a common and dangerous condition which occurs only in pregnancy (or immediately after birth) and can affect both mother and baby. Little is known about the cause of pre-eclampsia and there is currently no effective treatment except to deliver the baby early. In a previous grant from Action Research, these researchers discovered that normal pregnancy excites an intense inflammatory response in the mother and that pre-eclampsia arises when the response is excessive. In this new project, they will investigate the role of one key cellular messenger (nitric oxide) on the impact of the inflammatory response, to provide information which should help to develop better ways of diagnosing and treating the condition.