Preventing Hydrocephalus and Cerebral Palsy | Action Medical Research | Children's Charity

Premature babies ­ preventing hydrocephalus and cerebral palsy

This research was completed on 14 July 2003

Project LeaderProfessor Andrew G L Whitelaw MD FRCPCH, Dr Marianne Thoresen PhD FRCPCH and Dr Helen J Porter MD FRCPath
LocationDivision of Child Health, University of Bristol Medical School, Southmead Hospital in conjunction with Departments of Child Health and Paediatric Pathology St Michael's Hospital, Bristol.
Grant awarded26 October 2000
Start date12 March 2001
End date14 July 2003
Grant amount£114,470.00
Grant codeSP3654

We do not provide medical advice. If you would like more information about a condition or would like to talk to someone about your health, contact NHS Choices or speak to your GP. Please see our useful links page for some links to health information, organisations we are working with and other useful organisations. We hope you will find these useful. We are not responsible for the content of any of these sites.

One of the serious complications of premature birth is bleeding into the ventricles of the brain. This can give rise to hydrocephalus (water on the brain), often resulting in cerebral palsy and multiple disability, affecting several hundred babies a year in the UK. Previous treatments for hydrocephalus have been frustrating and many babies have to depend on an implanted device (shunt) to redirect the excess fluid elsewhere in their body. This team is investigating the 'signal molecule' which produces the scarring around the brain thought to be responsible for causing hydrocephalus. By injecting an antibody which can specifically block this signal molecule, they hope to prevent this complication and thereby avoid the need for shunt surgery.

Help us spread the word