Preterm delivery – how does progesterone prevent it?
This research was completed on 9 October 2007
|Project Leader||Professor J E Norman MD, MRCOG|
|Location||Division of Developmental Medicine and Division of Inflammation, Infection and Immunity, at Glasgow Royal Infirmary and Division of Inflammation, Infection and Immunity, Western Infirmary all at University of Glasgow.|
|Grant awarded||7 July 2005|
|Start date||10 October 2005|
|End date||9 October 2007|
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About 50,000 babies are born preterm each year in the UK. Preterm birth is the single biggest cause of disability, including blindness, deafness, severe developmental delay and cerebral palsy. Preventing preterm labour and delivery would have a major impact in averting lifelong disability in babies.These researchers want to study how the hormone progesterone can prevent pre-term delivery. During labour, white blood cells are activated and travel into the womb, where they play an important role in the process of giving birth. Progesterone appears to control the activity of these white blood cells. The team hopes that by understanding more about how and why the white cells are activated, they might be able to find better ways of preventing preterm labour.