Preterm labour and links to infection
This research was completed on 30 March 2007
|Project Leader||Dr M H F Sullivan PhD|
|Location||Department of Obstetrics and Gynaecology, Institute of Reproductive and Developmental Biology and Department of Paediatrics, Imperial College London|
|Grant awarded||29 October 2004|
|Start date||31 March 2005|
|End date||30 March 2007|
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Very premature infants are at high risk of problems that affect their brains, lungs, and immune systems. The brains of these tiny babies seem particularly vulnerable, and life-long disability may result. Treatment of preterm labour is generally of limited effectiveness, and once the babies are born, dealing with the subsequent complications is difficult, as many organs may be affected in each infant. Recent work has suggested that one species of bacteria may be of critical importance in preterm labour. The aim of this research project is to study the effects of this bacterium on the membranes surrounding the unborn baby. This should provide vital information to understand the link between preterm labour and infection and in the long term may lead to more effective treatments to prevent preterm birth.