60 years of top medical research investment across the East Midlands to help prevent suffering of sick babies and children
Children’s charity Action Medical Research is celebrating investing more than £100 million into vital medical research over the past 60 years, which has led to some key scientific breakthroughs to help reduce the suffering of sick babies and children.
Research funded over the years has included pioneering work carried out across the East Midlands including Nottingham and Leicester. Important research into devastating conditions is still being funded in the region today – see below for a full list of current projects.
The charity was originally founded in 1952, by Duncan Guthrie, in his quest to find a cure for polio, a condition that blighted the lives of many thousands of children including his own daughter Janet. Early research funded by the charity led to the development and rapid adoption of the first oral polio vaccine which eradicated new cases of the disease in the UK.
Since then the charity has developed an extraordinary track record in supporting some of the most significant medical breakthroughs in recent history – breakthroughs that have helped save thousands of children’s lives and changed many more.
Over the last six decades, Action Medical Research has awarded hundreds of grants and Research Training Fellowships to top scientists at institutions across England, Scotland, Wales and Northern Ireland.
Key successes achieved through the years include:
• helping introduce ultrasound scanning in pregnancy
• discovering the importance of taking folic acid before and during pregnancy to prevent spina bifida
• developing an infra-red scanner to help minimise risk of brain damage in babies
• developing a new state-of-the-art fetal heart rate monitor to make pregnancy safer for babies at risk
• helping to show that cooling the brain can minimise brain damage in some newborn babies deprived of oxygen at birth, reducing risk of death and severe disability.
• supporting the lead researcher whose team helped establish a vaccine for meningitis
• testing the early rubella vaccine – which was part of the first MMR vaccine.
Professor David Edwards, a pioneer in the development of treatments for newborn babies with brain damage, said: “The work supported by Action Medical Research at hospitals and universities over the decades has had a great impact on the lives of babies and children.
“The breadth and diversity of research supported in the past 60 years clearly demonstrates the importance of the funding this charity has provided. They have also supported the research careers of our most promising young doctors and scientists, many of whom have gone onto great success as a result.
“Without the support given by Action Medical Research over the past 60 years, the research and the subsequent medical breakthroughs and treatments which save lives, simply wouldn’t have been possible. I am sure they will continue to fund vital research and make a difference to the lives of babies and children for many years to come.”
Although the research we have funded has helped save and change so many children’s lives, there is still so much more to learn about what triggers diseases, how to prevent them and how to develop effective new treatments and find the best ways to care for sick babies and children. Today, Action Medical Research plays a vital role as the leading UK-wide medical research charity dedicated to helping babies and children.
The charity currently awards around £3 million in grants and Research Training Fellowships every year, funding around 70 research projects at any one time. Current projects being supported by the charity in the East Midlands includes:
Pre-term infants – developing movement skills
University of Nottingham with University College London
Juvenile arthritis and diabetes in childhood – University of Leicester
Prematurity and mathematics disabilities
University of Leicester and University College London
Preterm labour – the role of inflammation
University of Nottingham with the University of Edinburgh
While most mums worry about their child picking up bugs at nursery, for Debbie, from Northampton, it is a very real fear. If two-year-old son Malachi picks up a bug he can end up in hospital. Even when he is well he has a daily routine of medication and physiotherapy because he has a rare condition called Primary Ciliary Dyskinesia (PCD).
Children with PCD have abnormal cilia – tiny hair-like projections, which line the airways and ears. Cilia are supposed to beat rapidly, to sweep germs and dust out of the lungs. In PCD patients cilia don’t work properly. Mucus and bacteria build up in the airways, making children susceptible to infection and congestion and can lead to serious lung problems. Debbie said: “Malachi is on a nebuliser three times a day, he also has oral antibiotics and physiotherapy twice a day as well as inhalers. He is an active wilful little boy who is full of character and it can be very hard getting him to sit still for his nebuliser and physio!”
Action Medical Research - the leading UK-wide medical research charity dedicated to helping babies and children - is celebrating 60 years of vital research in 2012. We’ve been funding medical breakthroughs since we began in 1952 and have spent more than £100 million on research that has helped save thousands of children’s lives and changed many more. Today, we continue to find and fund the very best medical research to help stop the suffering of babies and children caused by disease and disability. We want to make a difference in:
• tackling premature birth and treating sick and vulnerable babies
• helping children affected by disability, disabling conditions and infections
• targeting rare diseases that together severely affect many forgotten children
But there is still so much more to do. Make 2012 a special year and help fund more life-changing research for some of the UK’s sickest babies and children.