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Latest research

2017 Research Projects

We are funding over 65 projects (including Research Training Fellowshipsat leading hospitals, universities and specialist centres across the UK. Projects we’ve funded over the past 12 months include research into preterm birth, spina bifida, cystic fibrosis, congenital heart disease, developmental language disorder, Crohn’s disease and several rare inherited conditions including neurodevelopmental disorders.

Winter 2017

Preventing neural tube defects £189,516 grant awarded for a 28 month project.  Led by Professor Greene, UCL Great Ormond Street Institute of Child Health, University College London.

Reducing the impact of congenital heart disease on brain development £174,035 grant awarded for a 30 month project.  Led by Professor Counsell, St Thomas' Hospital, King's College London.

Developing a new test to identify women at risk of premature birth £200,000 grant awarded for a two year project.  Led by Dr Tribe, St Thomas' Hospital, King's College London.

Cystic kidney disease - finding new drug treatments £199,786 grant awarded for a three year project.  Led by Professor Johnson, St James' University Hospital, University of Leeds.

Cystic fibrosis: improving treatment for lung infections £179,835 grant awarded for a three year project.  Led by Dr Bharat, University of Oxford.

Preventing brain injury in premature babies £141,949 grant awarded for a two year project.  Led by Professor Peebles, University College London.

Improving the treatment of traumatic brain injuries £147,357 grant awarded for a three year project.  Led by Dr  Agrawal, Addenbrooke’s Hospital, Cambridge.

Pelizaeus-Merzbacher disease – finding new treatments £84,447 grant awarded for a one year project. Led by Professor  Rowitch, University of Cambridge.

Summer 2017

Developmental delay and learning difficulties: spotting problems early so young children can get the help they need £70,698 grant awarded for a one year project.  Led by Professor Johnson, University of Leicester. 

Premature birth: helping babies whose early arrival has put them at risk of future anxiety £185,999 grant awarded for a three year project.  Led by Dr Nosarti, King’s College London.

Amblyopia: testing a new 3D movie treatment for lazy eye £177,932 grant awarded for a 22 month project.  Led by Dr Dahlmann-Noor, University College London.

Craniosynostosis: improving treatment for children £160,610 grant awarded for a two year project.  Led by Dr Jenkins, Great Ormond Street Institute of Child Health, University College London.

Developmental Language Disorder: understanding the genes involved to help improve children’s lives  £195,500 grant awarded for a three year project.  Led by Dr Paracchini, University of St Andrews.

Scarlet fever: reducing the spread of infection to help lower the risk of more serious life-threatening diseases £188,536 grant awarded for a two year project.  Led by Professor Sriskandan, Imperial College London.

Cerebral palsy: does it benefit children to stand up and exercise during lessons? £144,436 grant awarded for a 21 month project.  Led by Professor Dawes, Oxford Brookes University.

Research Training Fellowships 2017/2018

Our Research Training Fellowship scheme is 45 years old and we have now funded 177 fellowships at a total value of over £13 million.

Our latest Research Training Fellows are carrying out research in the following areas:

Mitochondrial disease – investigating gene therapy  Dr N Keshavan of  the Genetics and Genomic Medicine Programme, UCL Great Ormond Street Institute of Child Health was awarded £229,924 to investigate gene therapy for mitochondrial DNA depletion syndrome.

What causes Crohn’s disease? Dr J Ashton of the Human Development and Health Department,  Southampton General Hospital and University of Southampton was awarded £240,640 to investigate functional and interpretive analysis of the microbiome and assessment of ileal transcriptome and genetic interactions in paediatric Crohn's disease.

Congenital heart disease - improving surgical treatment  Dr E Sauvage of the Centre for Cardiovascular Imaging, University College London and Institute of Cardiovascular Science, Great Ormond Street Hospital for Children, London was awarded £155,516 to carry out a study entitled  PATCH – Patient-specific Treatment of Congenital Heart Disease.

None of our work would be possible without the generosity of people who make donations, raise funds and take part in events, as well as our trust and corporate partners.

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